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【作业】第三单元 基因和染色体-2(基因概念的多样性) Chapter 2 Gene and Chromosome_ Homework

1、 问题:请上传Chapter 2 Gene and Chromosome上直播课和慕课过程中所记的笔记(可以是提纲式或是思维导图,需要记录重点和难点,特别要记录下英文PPT中的专业单词,笔记请纸质记录,拍照后上传)    要求:1. 有章节题目;2. 要点大纲;3. 记录下重点难点;4. 可以用思维导图式;5. 记录下英文专业词汇;6. 不能出现个人信息。
评分规则: 【 100-99:有章节题目和要点大纲,逻辑清楚,内容完整详细,重点难点突出,有记下英文专业词汇,且书写工整;90-89: 有章节题目和要点大纲,逻辑清楚,内容完整,有重难点,但不突出,只有少数英文词汇;书写工整;80-79:有章节题目和要点大纲,逻辑清楚,但内容和重难点不够完整,没有英文词汇,书写不够工整;70-69:有章节题目,但是逻辑不清楚,但内容和重难点不够完整,没有英文词汇,书写不工整,版面很乱60:有交笔记,但是内容非常让人不满意。0:没有提交笔记

第三单元 基因和染色体-2(基因概念的多样性) Chapter 2 Gene and Chromome _ Test

1、 问题:Watson & Crick won the noble prize in 1962 for their discoveries concerning:
选项:
A:the interaction between tumour viruses and the genetic material of the cell
B:the mobile genetic elements
C:the molecular structure of nucleic acids
D:the invention of the PCR method
答案: 【the molecular structure of nucleic acids

2、 问题:Most of the stability of the double-stranded DNA structure is the result of
选项:
A: hydrogen bonding between purines.
B:the phosphodiester backbone.
C:the angle of the planes of the bases with respect to the helix axis.
D:the stacking interactions between base pair.
答案: 【the stacking interactions between base pair.

3、 问题:It is easier to melt DNA richer in AT than GC because
选项:
A:it is more heat sensitive.
B:there is one less hydrogen bond in an AT base pair
C: the helix pitch is longer in AT rich regions.
D:All of the three statements.
答案: 【there is one less hydrogen bond in an AT base pair

4、 问题:As B-DNA is gradually heated, the absorbance at 260 nm
选项:
A:increases.
B:decreases.
C:stays the same.
D: It is unpredictable.
答案: 【increases.

5、 问题:What are the target and the probe of the Southern blotting?
选项:
A:DNA, DNA
B:RNA, RNA
C:Protein, antibody  
D: None of the above.
答案: 【DNA, DNA

6、 问题:Supercoiling of pure circular DNA is a result of __. 
选项:
A:underwinding or overwinding of the helix
B:the long length of the strands
C:the lack of associated histones 
D:the activity of exonucleases
答案: 【underwinding or overwinding of the helix

7、 问题:Which of the following is an example of highly-repetitive DNA?
选项:
A:Globin gene family 
B:Histone gene cluster
C:Minisatellite DNA
D:rDNA gene family
答案: 【Minisatellite DNA

8、 问题:Histones are found in close association with DNA. Which of the following statements is incorrect?
选项:
A:A nucleosome core is composed of ~146 bp of DNA and a histone octamer.
B:Histone H1 binds to linker DNA.
C:There are only four types of histones.
D:Nucleosomes are evenly distribution within chromatin.
答案: 【There are only four types of histones.

9、 问题:DNA wraps around an octamer of histones to form bead-like structures called __.
选项:
A:nucleoids
B:nucleosomes
C:nucleoli
D:chromatids
答案: 【nucleosomes

10、 问题:What is the approximate diameter of a chromatin fiber?
选项:
A:3 nm 
B:30 nm
C:300 nm  
D:3 mm
答案: 【30 nm

11、 问题:What is the order of packaging of chromatin in eukaryotic cells from smallest to largest size?
选项:
A:double-helix → solenoid螺线管 → nucleosome → chromosome
B:double-helix → chromatin → solenoid → chromosome
C:single-stranded DNA → chromatin → histones → chromosome
D:double-helix → nucleosomes → solenoid → chromosome
答案: 【double-helix → nucleosomes → solenoid → chromosome

12、 问题:How might mitochondrial DNA be distinguished from eukaryotic nuclear DNA?
选项:
A:Mitochondrial DNA is in the Z conformation, nuclear DNA is in the B conformation.
B:Mitochondrial DNA is methylated, nuclear DNA is not.
C:Nuclear DNA is linear, mitochondrial DNA are circular.
D:They cannot be distinguished and must be clearly separate during purification
答案: 【Nuclear DNA is linear, mitochondrial DNA are circular.

13、 问题:Which of the following statements is not correct concerning to the prokaryotic genome and eukaryotic genome?
选项:
A:There are many non-coding DNAs in eukaryotic genome.
B:DNA are almost naked in prokaryotes.
C:There are many operons in eukaryotic genome.
D:Prokaryotic genome is a single circular DNA molecule.
答案: 【There are many operons in eukaryotic genome.

14、 问题:Which does not apply to most bacterial DNA? 
选项:
A:Circular.  
B:Relaxed. 
C:Not packed into nucleosomes. 
D:Supercoiled. 
答案: 【Relaxed. 

15、 问题:In a nucleic acid molecule, nucleotides are joined into a polymer by the __ phosphodiester bonds.
选项:
A:2′,3′  
B:2′,4′ 
C:3′, 4′ 
D:3′, 5′
答案: 【3′, 5′

16、 问题:All genomes are composed of DNA. 
选项:
A:正确
B:错误
答案: 【错误

17、 问题:The two strands of double-stranded DNA have the same content of each of the bases A, T, G and C.
选项:
A:正确
B:错误
答案: 【错误

18、 问题:The supercoiling of double-stranded circular DNA can be removed by cleaving a single phosphodiester bond on only one strand (nick). 
选项:
A:正确
B:错误
答案: 【正确

19、 问题:Prokaryotic DNA is organized into protein-DNA structures called nucleoids. 
选项:
A:正确
B:错误
答案: 【正确

20、 问题:Histone H1 is part of the histone octamer.
选项:
A:正确
B:错误
答案: 【错误

21、 问题:Heterochromatin make up most of the genome.
选项:
A:正确
B:错误
答案: 【错误

22、 问题:The maximum C-value is always greater than minimum C-value in an organism.
选项:
A:正确
B:错误
答案: 【错误

【作业】第四单元 DNA的复制 Chapter 3 DNA replication-homework

1、 问题:请上传Chapter 3 DNA replication上直播课和慕课过程中所记的笔记(可以是提纲式或是思维导图,需要记录重点和难点,特别要记录下英文PPT中的专业单词,笔记请纸质记录,拍照后上传)    要求:1. 有章节题目;2. 要点大纲;3. 记录下重点难点;4. 可以用思维导图式;5. 记录下英文专业词汇;6. 不能出现个人信息。
评分规则: 【 100-90:有章节题目和要点大纲,逻辑清楚,内容完整详细,重点难点突出,有记下英文专业词汇,且书写工整;89-80: 有章节题目和要点大纲,逻辑清楚,内容完整,有重难点,但不突出,只有少数英文词汇;书写工整;79-70:有章节题目和要点大纲,逻辑清楚,但内容和重难点不够完整,没有英文词汇,书写不够工整;69-61:有章节题目,但是逻辑不清楚,但内容和重难点不够完整,没有英文词汇,书写不工整,版面很乱60:有交笔记,但是内容非常让人不满意。0:没有提交笔记

第四单元 DNA的复制 Chapter 3 DNA replication -test

1、 问题:All of the following statements about DNA replication in prokaryotes are true except:
选项:
A:DNA replication is conservative.
B:DNA synthesis occurs in the 5’ to 3’ direction.
C:Requires a 3’OH to initiate replication which is provided by an RNA primer.
D: DNA replication initiate from specific origin. 

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