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本课程起止时间为:2021-03-25到2021-07-31

Chapter 1 The structure and function of nucleic acid The structure and function of nucleic acid

1、 问题: Which of the following are pyrimidines?
选项:
A: adenine and cytosine
B:adenine and guanine 
C:adenine and thymine
D: cytosine and thymine
E:guanine and thymine
答案: 【 cytosine and thymine

2、 问题: Which kind of nucleotide does not exist in DNA?
选项:
A:dAMP
B:dTMP
C:dUMP
D:dGMP
E:dCMP
答案: 【dUMP

3、 问题: Which of the following is the
connection of primary structure of nucleic acid molecule?
选项:
A:2 ′, 3 ′ phosphodiester bond
B:3 ′, 5 ′ phosphodiester bond
C: 2 ′, 5 ′ phosphodiester bond  
D: glycosidic bond
E:hydrogen bond
答案: 【3 ′, 5 ′ phosphodiester bond

4、 问题: In
nucleotide molecule, which carbon atom of ribose and the purine N9
linked by glycosidic bond?
选项:
A:C-1 ‘
B:C-2 ‘
C:C-3 ‘
D:C-4 ‘
E:C-5 ‘
答案: 【C-1 ‘

5、 问题: Which
of the following may be right if a nucleic acid has the following base composition: A
= 16%, G= 39%, C = 22%, T= 23% (C)?
选项:
A:double strand DNA
B: tRNA
C:single strand DNA
D:single strand RNA
E:double strand RNA
答案: 【single strand DNA

6、 问题:Which of the following refers to melting temperature of DNA?
选项:
A: The
temperature when A260 reached the
maximum
B:The temperature when A260 reaches
the maximum value of 50%
C: DNA
begin unwinding of temperature
D:The complete unwinding DNA
strands of the temperature
E:The temperature when A280 reaches
the maximum value of 50%
答案: 【The temperature when A260 reaches
the maximum value of 50%

7、 问题: In nucleic acid molecules, which of the following is the key part that the genetic information is stored in?
选项:
A:pentose conformation
B:The rotation angle of bases
C: The base sequence
D:pentose phosphate backbone
E:phosphate ester bond
答案: 【 The base sequence

8、 问题:Which are correct about the descriptions of nucleic acid
molecular hybridization?
选项:
A:It refers to renaturation of denatured DNA
B:DNA can be
hybridized with RNA to form a double helix 
C:RNA can be
hybridized with its encoded polypeptide chain 
D: It can detect the homology
between hybrid nucleic acids
E: ‍DNA or RNA
from different sources can be hybridized as long as some bases can pair 
答案: 【DNA can be
hybridized with RNA to form a double helix ;
 It can detect the homology
between hybrid nucleic acids;
 ‍DNA or RNA
from different sources can be hybridized as long as some bases can pair 

9、 问题:Which are correct about the descriptions of mRNA?
选项:
A:Among the three RNAs, the metabolic rate is the fastest‍
B:The
secondary structure contains local double helix
C: It consists of
two subunits
D:There are m7Gppp cap
and polyA tail
E:It contains genetic information
答案: 【Among the three RNAs, the metabolic rate is the fastest‍;
The
secondary structure contains local double helix;
There are m7Gppp cap
and polyA tail;
It contains genetic information

10、 问题:The sequence of a DNA strand is 5 ‘- A-T-T-C-3’, which
can be its complementary strand?
选项:
A:5′-T-A-A-G-3′
B:5′-T-C-C-G-3′
C:5′-G-A-A-T-3′
D:5′-U-A-A-G-3′
E:5′-G-A-A-U-3′
答案: 【5′-G-A-A-T-3′;
5′-G-A-A-U-3′

【作业】Chapter 1 The structure and function of nucleic acid The structure and function of nucleic acid

小提示:本节包含奇怪的同名章节内容

1、 问题:What is the background and significance of
DNA double helix structure? What inspiration can you get from it?
评分规则: 【 double strand helix model:
inspiration you will get from this chapter

2、 问题:What is the structure of nucleosome?What is the key points of DNA double helix?
评分规则: 【 What is the structure of nucleosome?
What is the key points of DNA double helix?

【作业】Chapter 1 The structure and function of nucleic acid The structure and functio of nucleic acid

1、 问题:What is the structure of nucleosome?What is the key points of DNA double helix?
评分规则: 【 What is the structure of nucleosome?
What is the key points of DNA double helix?

Chapter 2 DNA replication DNA replication

1、 问题:Which
statement is correct about DNA pol in prokaryotes
选项:
A:DNA-pol I
is the major DNA replicase
B:DNA-pol II has highest activity, is the major enzyme in DNA replication
C: DNA-pol III is the major DNA replicase, and has the 3′→5′ exonuclease activity
D: DNA-pol III seal the nick during replication and repair
E:DNA-pol II has 5′→3′ exonuclease activity
答案: 【 DNA-pol III is the major DNA replicase, and has the 3′→5′ exonuclease activity

2、 问题:The
function of DNA topoisomerase is
选项:
A:to stable
unwound DNA duplex
B:to recognize replication origin site
C: to synthesize RNA primer
D: to unwind DNA duplex, in order to replicate
E:to unwind DNA super coil, avoid tangling together
答案: 【to unwind DNA super coil, avoid tangling together

3、 问题:Which
process doesn’t require DNA ligase
选项:
A:DNA damage repairing
B:reverse transcription
C:DNA replication
D:DNA recombination
E:genetic engineering
答案: 【reverse transcription

4、 问题:The
function of RNA primer is
选项:
A:to separate DNA double helix
B:to provide 3′-OH to synthesize DNA molecule
C:to provide 5′-P to synthesize DNA molecule
D:to provide 5′-P to synthesize RNA molecule

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