2022 Pharmacology in practice(Zhejiang University) 最新满分章节测试答案

文章目录[隐藏]

Chapter 1 Introduction to experimental pharmacology Quiz
Chapter 2 The effects of drugs on guinea pig ileum Quiz
Chapter 3 Effects and underlying mechanisms of adrenergic receptor agonists on arterial blood pressu
Chapter 4 Effect of liver injury on the action of propofol Quiz
Chapter 5 Anticonvulsive effect of sodium phenobarbital on the nikethamide induced convulsion Quiz
Chapter 6 Writing prescription and monitoring drug efficacy Quiz
Chapter 7 Acute drug toxicity and drug safety Quiz
Chapter 8 Case discussion of Clinical Use of Antibiotics Quiz

本答案对应课程为:点我自动跳转查看
本课程起止时间为:2022-04-21到2022-06-30

Chapter 1 Introduction to experimental pharmacology Quiz

1、问题:For a short transfer, mice are gripped by its
选项：
A:tail tip
B:base of tail
C:tail
D:back skin
答案: 【base of tail 】

2、问题:Regarding the restraint of mice, which of the following statements is incorrect
选项：
A:The mouse is placed on a smooth surface is easier to grasp
B:The left thumb and index finger to fix the mouse ear and head skin, ring finger pinky and palm fixed back and tail
C: It is best to wear gloves to prevent scratching
D:Do not grasp the skin of the neck too tightly to prevent the animal from suffocation and death
答案: 【The mouse is placed on a smooth surface is easier to grasp】

3、问题:When the mice were gavaged
选项：
A:If resistance is found after needle insertion, the liquid can be injected directly
B: It is best to insert the needle from the center of the mouth
C:It is necessary to inject the drug after all the gavage needles are inserted into the mouse body
D:Mice should be fully straightened to keep the body in a straight line
答案: 【Mice should be fully straightened to keep the body in a straight line】

4、问题:The common gavage volume for mice is
选项：
A:1~3ml/10g
B:5~10 ml/10g
C:0.1~0.2 ml/10g
D:0.5~1 ml/10g
答案: 【0.1~0.2 ml/10g】

5、问题:Regarding the route of administration in mice, which of the following statements is false
选项：
A:Animals were fasted for a period of time prior to administration in experiments using gavage
B:Tail vein injection in mice should start at the base of the tail
C:During gavage administration, if the animal struggles violently, the intragastric needle should be withdrawn and then injected
D:During intraperitoneal injection, the needle should not be penetrated too deep or too high, so as not to damage the internal organs
答案: 【Tail vein injection in mice should start at the base of the tail】

Chapter 2 The effects of drugs on guinea pig ileum Quiz

1、问题:In the isolated intestinal muscle experiment, the statistical analysis method used to analyze the effect of atropine on the contraction effect of intestinal muscle due to acetylcholine is
选项：
A:chi-square test
B:t-test
C:analysis of variance
D: Fisher’s exact probability method
答案: 【t-test】

2、问题:To record the contractile tone of isolated intestinal muscles, what change in intestinal muscle activity occurs after the addition of atropine and then barium chloride to Tait’s solution？
选项：
A:No change in intestinal muscle activity after the addition of atropine and then barium chloride
B:After the addition of atropine, the intestinal muscle is relaxed, and after the addition of barium chloride, the intestinal muscle remains in a relaxed state
C:After the addition of atropine, the intestinal muscle contracted, and then added barium chloride, the intestinal muscle activity was in a relaxed state
D:After the addition of atropine, the intestinal muscle was relaxed, and then after the addition of barium chloride, the intestinal muscle activity was in a contracted state
答案: 【After the addition of atropine, the intestinal muscle was relaxed, and then after the addition of barium chloride, the intestinal muscle activity was in a contracted state】

3、问题:The mechanism by which histamine causes contraction of guinea pig ileal smooth muscle is
选项：
A:agonize H1 receptors of smooth muscle cell membrane
B:agonize M receptors of smooth muscle cell membrane
C:agonize N receptors of smooth muscle cell membrane
D:blocking e H1 receptors of smooth muscle cell membran
答案: 【agonize H1 receptors of smooth muscle cell membrane】

4、问题:In an isolated intestinal muscle perfusion system, to investigate whether the contractile effect of a drug on the intestinal muscle is mediated by M receptors, one should
选项：
A:add the drug to be tested first, observe the contraction curve, then add atropine, and observe the effect
B:add atropine first, observe the contraction curve, then add the drug under test, and observe the effect
C:Add atropine, observe the contraction curve, elute, then add the drug to be tested, and observe the effect
D:Add the drug to be tested, observe the contraction curve, elute, add atropine, then add the drug to be tested and observe the effect
答案: 【Add the drug to be tested, observe the contraction curve, elute, add atropine, then add the drug to be tested and observe the effect】

5、问题:The reason why the contents of the intestinal lumen must be flushed in the pretreatment of intestinal muscle specimens is
选项：
A:the contents will prevent contact between the drug and the receptor
B: the contents promote spontaneous peristalsis of the ileum
C:the contents increase the self-weight of the specimen and affect the basal tone of the intestinal muscle
D:The contents can escape from the intestinal lumen into the Tylenol and affect the drug effect
答案: 【 the contents promote spontaneous peristalsis of the ileum】

Chapter 3 Effects and underlying mechanisms of adrenergic receptor agonists on arterial blood pressu

1、问题:Which kind of method was used for blood pressure measurement in this experiment
选项：
A:Invasive assay
B:Non-invasive assay
C:Wireless assay
D:Wired assay
答案: 【Invasive assay】

2、问题:In this experiment, epinephrine was administrated via
选项：
A:ear marginal vein injection
B:intraperitoneal injection
C:tail vein injection
D:muscle injection
答案: 【ear marginal vein injection】

3、问题:In this experiment, the anesthetic was administrated via
选项：
A:ear marginal vein injection
B:intraperitoneal injection
C:tail vein injection
D:muscle injection
答案: 【ear marginal vein injection】

4、问题:After the experiment, we gave a small conclusion that isoprenaline decrease blood pressure may occur through activation of
选项：
A:α adrenergic receptor
B:β adrenergic receptor
C:Muscrinic receptor
D:Nicotinic receptor
答案: 【β adrenergic receptor】

5、问题:According to the results of the experiment, noradrenaline decrease blood pressure may occur through activation of
选项：
A:α adrenergic receptor
B:β adrenergic receptor
C:Muscrinic receptor
D:Nicotinic receptor
答案: 【α adrenergic receptor】

Chapter 4 Effect of liver injury on the action of propofol Quiz

1、问题:The processes of pharmacokinetics do not include
选项：
A:Absorption
B:Binding with receptors
C:Distribution
D:Metabolism
答案: 【Binding with receptors】

2、问题:Inhibition of metabolism of a drug could induce
选项：
A:Increased pharmacological activity of the drug