2022知到答案 药理学(南开大学) 最新完整智慧树知到满分章节测试答案
第一章 单元测试
1、 问题:
Which of the following drugs is an inducer of CYP1A2 ( )
选项:
A:Tobacco
B:Ciprofloxacin
C:Fluconazole
D:Simvastatin
答案: 【
Tobacco
】
2、 问题:
The process of renal excretion of drugs does not include which of the following options ( )
选项:
A:Glomerular filtration
B:Hepatoenteric circulation
C:Active secretion of renal tubules
D:passive tubule reabsorption
答案: 【
Hepatoenteric circulation
】
3、 问题:
Which of the following statements is false ( )
选项:
A:Tmax refers to the time that takes a drug or other substance to reach the maximum concentration Cmax
B:The time required to reach half of Cmax by oral administration is different from the time required for half of Cmax intravenously
C:T half (T1/2)of a drug refers to the time required for the plasma concentration of the drug to drop by half
D:AUC refers to Area under the curve (pharmacokinetics), regarding plasma drug concentration-time curves
答案: 【
The time required to reach half of Cmax by oral administration is different from the time required for half of Cmax intravenously
】
4、 问题:
The main factors affecting drug absorption are ( )
选项:
A:The first pass effect
B:pH value
C:Blood flow
D:Administration route
答案: 【
The first pass effect
pH value
Blood flow
Administration route
】
5、 问题:
The bioavailability of the drug refers to ( )
选项:
A:The fraction or percentage of a drug that reaches hepatic portal circulation
B:The relative speed of the drug absorption into the body
C:The fraction or percentage of a drug that reaches the action point
D:The fraction or percentage of a drug that reaches systemic circulation
答案: 【
The fraction or percentage of a drug that reaches systemic circulation
】
第二章 单元测试
1、 问题:
Which of the following options is wrong about the antagonist ( )
选项:
A:Antagonists are drugs that decrease or oppose the actions of another drug or endogenous ligand
B:A competitive antagonist binds to the different site as the endogenous signaling molecule, blocking its binding site at the receptor
C:Antagonist are typically classified as competitive and non-competitiv
D:Antagonist have binding affinity to receptor but they have no intrinsic activit
答案: 【
A competitive antagonist binds to the different site as the endogenous signaling molecule, blocking its binding site at the receptor
】
2、 问题:
Which of the following statements is wrong ( )
选项:
A:The higher the therapeutic index, the safer the drug, as the risk of a toxic or lethal overdose decreas
B:The potency not only depends on the efficacy of a drug, but also on its binding affinity at the target site
C:Effective dose (ED) refers to the minimal drug amount required to achieve the maximum effect
D:The ratio of ED50 to LD50 is termed the therapeutic index and differs for each drug
答案: 【
The ratio of ED50 to LD50 is termed the therapeutic index and differs for each drug
】
3、 问题:
The therapeutic index refers to ( )
选项:
A:LD50/ED50
B: LD5/ED95
C: ED95/LD5
D: ED50/LD5
答案: 【
LD50/ED50
】
4、 问题:
If a drug binds to a receptor and produces some biologic responses that mimics the response to the endogenous ligand, the drug belongs to ( )
选项:
A:Stimulant
B:Inhibitor
C:Agonist
D:Antagonist
答案: 【
Agonist
】
5、 问题:
Which of the following statements about the receptor is correct?
选项:
A:Receptor refers to a protein that binds to a ligand and produces a measurable response
B:Receptors are polysaccharides on the cell membrane
C:The effects caused by the binding of receptors and ligands or agonists are excitatory effects
D:All drugs work by stimulating or blocking the corresponding receptors
答案: 【
Receptor refers to a protein that binds to a ligand and produces a measurable response
】
第三章 单元测试
1、 问题:
Which of the following options belongs to selective β1 blockers ( )
选项:
A:Atenolol
B:Metoprolol
C:Acebutolol
D:Labetalol
答案: 【
Labetalol
】
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