2022知到答案 药理学（南开大学） 最新完整智慧树知到满分章节测试答案

第一章 单元测试

1、 问题:

Which of the following drugs is an inducer of CYP1A2 (    )

选项：
A:Tobacco 
B:Ciprofloxacin
C:Fluconazole
D:Simvastatin
答案: 【
Tobacco 
】

2、 问题:

The process of renal excretion of drugs does not include which of the following options (    )

选项：
A:Glomerular filtration 
B:Hepatoenteric circulation
C:Active secretion of renal tubules
D:passive tubule reabsorption
答案: 【
Hepatoenteric circulation
】

3、 问题:

Which of the following statements is false (    )

选项：
A:Tmax refers to the time that takes a drug or other substance to reach the maximum concentration Cmax
B:The time required to reach half of Cmax by oral administration is different from the time required for half of Cmax intravenously
C:T half （T1/2）of a drug refers to the time required for the plasma concentration of the drug to drop by half
D:AUC refers to Area under the curve (pharmacokinetics), regarding plasma drug concentration-time curves
答案: 【
The time required to reach half of Cmax by oral administration is different from the time required for half of Cmax intravenously
】

4、 问题:

The main factors affecting drug absorption are (     )

选项：
A:The first pass effect 
B:pH value
C:Blood flow
D:Administration route
答案: 【
The first pass effect 
pH value
Blood flow
Administration route
】

5、 问题:

The bioavailability of the drug refers to （   ）

选项：
A:The fraction or percentage of a drug that reaches hepatic portal circulation
B:The relative speed of the drug absorption into the body
C:The fraction or percentage of a drug that reaches the action point
D:The fraction or percentage of a drug that reaches systemic circulation
答案: 【
The fraction or percentage of a drug that reaches systemic circulation
】

第二章 单元测试

1、 问题:

Which of the following options is wrong about the antagonist (    )

选项：
A:Antagonists are drugs that decrease or oppose the actions of another drug or endogenous ligand
B:A competitive antagonist binds to the different site as the endogenous signaling molecule, blocking its binding site at the receptor
C:Antagonist are typically classified as competitive and non-competitiv
D:Antagonist have binding affinity to receptor but they have no intrinsic activit
答案: 【
A competitive antagonist binds to the different site as the endogenous signaling molecule, blocking its binding site at the receptor
】

2、 问题:

Which of the following statements is wrong （    ）

选项：
A:The higher the therapeutic index, the safer the drug, as the risk of a toxic or lethal overdose decreas
B:The potency not only depends on the efficacy of a drug, but also on its binding affinity at the target site
C:Effective dose (ED) refers to the minimal drug amount required to achieve the maximum effect
D:The ratio of ED50 to LD50 is termed the therapeutic index and differs for each drug
答案: 【
The ratio of ED50 to LD50 is termed the therapeutic index and differs for each drug
】

3、 问题:

The therapeutic index refers to （    ）

选项：
A:LD50/ED50 
B: LD5/ED95
C: ED95/LD5
D: ED50/LD5
答案: 【
LD50/ED50 
】

4、 问题:

If a drug binds to a receptor and produces some biologic responses that mimics the response to the endogenous ligand, the drug belongs to (    ) 

选项：
A:Stimulant 
B:Inhibitor
C:Agonist 
D:Antagonist
答案: 【
Agonist 
】

5、 问题:

Which of the following statements about the receptor is correct?

选项：
A:Receptor refers to a protein that binds to a ligand and produces a measurable response
B:Receptors are polysaccharides on the cell membrane
C:The effects caused by the binding of receptors and ligands or agonists are excitatory effects
D:All drugs work by stimulating or blocking the corresponding receptors
答案: 【
Receptor refers to a protein that binds to a ligand and produces a measurable response
】

第三章 单元测试

1、 问题:

Which of the following options belongs to selective β1 blockers (   )

选项：
A:Atenolol
B:Metoprolol
C:Acebutolol
D:Labetalol
答案: 【
Labetalol
】