2021 Medical Biochemistry(Shandong University) 最新满分章节测试答案

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本课程起止时间为:2021-02-26到2021-05-30
本篇答案更新状态:已完结

Chapter 1 Structure and Function of Proteins Unit test

1、 问题:The chemical bond between the A and B chains of insulin is
选项：
A:peptide bond
B:disulfide bond
C:phosphoester bond
D:ionic bond
E:hydrophobic force
答案: 【disulfide bond】

2、 问题:The characteristic of secondary structure in myoglobin is to have more
选项：
A:α-helix
B:β-pleated sheet
C:β-strand 
D:loop
E:βαβ motif
答案: 【α-helix】

3、 问题:Autoclave disinfection is to make bacterial proteins
选项：
A:denaturation
B:precipitation
C:ionization
D:dissolved
E:degradation
答案: 【denaturation】

4、 问题:The protein whose structural change can cause sickle cell anemia is
选项：
A:lactate dehydrogenase
B:pyruvate kinase
C:insulin
D:myoglobin
E:hemoglobin
答案: 【hemoglobin】

5、 问题:The amino acid that can form disulfide bond in protein structure is
选项：
A:Trp
B:Met
C:Cys
D:Pro
E:Ser
答案: 【Cys】

6、 问题:Protein denaturation is due to
选项：
A:conformation destruction of protein
B:depolymerization of protein subunits
C:proteolysis
D:changes in the primary structure of protein
E:breaking of peptide bonds
答案: 【conformation destruction of protein】

7、 问题:The amino acid without the asymmetric carbon atom is
选项：
A:Tyrosine
B:Serine
C:Glycine
D:Glutamate
E:Leucine
答案: 【Glycine】

8、 问题:At the isoelectric point, the protein behaves as
选项：
A:The molecular net charge is zero
B:The molecule most charged
C:Not easy to be precipitated
D:Increased solubility
E:Directional movement under the electrophoresis
答案: 【The molecular net charge is zero】

9、 问题:Which of the following amino acids is imino acid？
选项：
A:proline
B:histidine
C:glycine
D:tryptophan
E:lysine
答案: 【proline】

10、 问题:Which of the following amino acids does not exist in protein molecule
选项：
A:cysteine
B:histidine
C:citrulline
D:arginine
E:lysine
答案: 【citrulline】

11、 问题:Which of the following chemical bonds is involved in maintaining α-helix and β- pleated sheet？
选项：
A:peptide bond
B:ionic bond/salt bond
C:disulfide bond
D:hydrophobic effect
E:hydrogen bond
答案: 【hydrogen bond】

12、 问题:A solution contains the mixture of four kinds of protein, A, B, C and D, whose pI  are 6.0, 2.77, 9.74 and 5.07, respectively. The electrophoresis method is carried out to separate these four proteins in the electric field with pH=9.0 buffer. The sequence of the electrophoresis zone from the positive pole to the negative pole is as follows
选项：
A:A-B-C-D
B:B-D-A-C
C:B-D-C-A
D:D-B-A-C
E:B-A-D-C
答案: 【B-D-A-C】

13、 问题:Secondary structures of protein mainly include
选项：
A:α helix
B:β conformation
C:β turn
D:motif
E:random coil
答案: 【α helix;
β conformation;
β turn;
random coil】

14、 问题:Which of the following descriptions about tertiary structure of protein are correct?
选项：
A:All polypeptide chains with tertiary structure have biological activities.
B:Most hydrophilic groups are located on the surface of tertiary structure.
C:The stability of tertiary structure is maintained by covalent bonds.
D:Tertiary structure is three-dimensional arrangement of all atoms in a polypeptide chain.
E:Formation of tertiary structure is the result of interaction between side chain groups of a polypeptide chain.
答案: 【Most hydrophilic groups are located on the surface of tertiary structure.;
Tertiary structure is three-dimensional arrangement of all atoms in a polypeptide chain.;
Formation of tertiary structure is the result of interaction between side chain groups of a polypeptide chain.】

15、 问题:Compared with myoglobin, hemoglobin is characterized by
选项：
A:Having quaternary structure
B:Containing heme
C:Having cooperative effects between subunits during combination with oxygen
D:The oxygen dissociation curve is S-shaped.
E:The main function is to transport oxygen.
答案: 【Having quaternary structure;
Having cooperative effects between subunits during combination with oxygen;
The oxygen dissociation curve is S-shaped.;
The main function is to transport oxygen.】

16、 问题:The UV absorption properties of protein are due to the presence of
选项：
A:tryptophan
B:glutamic acid
C:tyrosine
D:aspartic acid
E:histidine
答案: 【tryptophan;
tyrosine】

17、 问题:Which of the following amino acids contain hydroxyl group?
选项：
A:serine
B:phenylalanine
C:tyrosine
D:threonine
E:methionine
答案: 【serine;
tyrosine;
threonine】

18、 问题:Which of the following descriptions about peptide unit are correct
选项：
A:Peptide unit is the basic unit forming the secondary structure of a polypeptide chain.
B:The six atoms that form peptide bond are in the same plane.
C:The bond length of peptide bond is between the length of single bond and double bond.
D:The single bond that connects to α-carbon atom can rotate freely.
E:The rotation angle between neighbor peptide units is affected by the side chains.
答案: 【Peptide unit is the basic unit forming the secondary structure of a polypeptide chain.;
The six atoms that form peptide bond are in the same plane.;
The bond length of peptide bond is between the length of single bond and double bond.;
The single bond that connects to α-carbon atom can rotate freely.;
The rotation angle between neighbor peptide units is affected by the side chains.】

19、 问题:When the pH > pI of protein, the proteins have positive charge.
选项：
A:正确
B:错误
答案: 【错误】