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本课程起止时间为:2021-03-01到2021-07-16

【作业】Chapter 1 Introduction Homework (Chapter 1 Introduction)

1、 问题:What is a drug?
评分规则: 【 Drugs are substances which alter or ascertain physiological function and pathological state, used for the purposes of prevention, diagnosis and treatment of diseases. 

Chapter 1 Introduction Quiz (Chapter 1 Introduction)

1、 问题:Which is wrong about the description of the drug?
选项:
A:A chemical substance
B:A chemical that interferes with cellular metabolic activity
C:A substance that affects the physiological functions of the body
D:Has the nourishment, the nutrition, the health care, the rehabilitation function material
答案: 【Has the nourishment, the nutrition, the health care, the rehabilitation function material

2、 问题:Pharmacology is an important subject in medical teaching because (     )
选项:
A:The mechanism of action of the drug was elucidated
B:Improve the quality of drugs, improve the efficacy of drugs
C:It provides experimental data and theoretical basis for the development of new drugs
D:It provides a theoretical basis for guiding rational drug use in clinical practice
答案: 【It provides a theoretical basis for guiding rational drug use in clinical practice

3、 问题:The method of pharmacology is experimental means (     )
选项:
A:Strictly control the condition and observe the law and principle of drug action on the body
B:Using animals for experimental research
C:The drug was studied in vitro and in vivo
D:The experimental data provided have important reference value for clinic
答案: 【Strictly control the condition and observe the law and principle of drug action on the body

4、 问题:Pharmacodynamics is research (     )
选项:
A:Clinical efficacy of drugs
B:Ways to improve the efficacy of drugs
C:How to improve drug quality
D:Drug action on the body and the mechanism of action
答案: 【Drug action on the body and the mechanism of action

5、 问题:Pharmacokinetics is research (     )
选项:
A:Drug changes in the body and their regularity
B:How do drugs affect the body
C:A rational medication regimen
D:The dynamic changes of drugs and their laws
答案: 【Drug changes in the body and their regularity

6、 问题:Pharmacology is research (   )
选项:
A:pharmacodynamics
B:pharmacokinetics
C:drug
D:Drug – body interaction and its law
答案: 【Drug – body interaction and its law

7、 问题:New drugs must be provided (     ) for clinical trials
选项:
A:Systematic pharmacological research data
B:Acute and chronic toxicity were observed
C:LD50
D:Preclinical data
答案: 【Preclinical data

8、 问题:The research object of pharmacology is
选项:
A:human body
B:body
C:Animal pathological model
D:healthy animal
答案: 【body

9、 问题:The research object of experimental pharmacology is
选项:
A:animal
B:human body
C:body
D:health volunteer
答案: 【animal

10、 问题:The research object of clinical pharmacology is
选项:
A:human body
B:body
C:Animal pathological model
D:health volunteer
答案: 【human body

【作业】Chapter 2 Pharmacokinetics Homework(Chapter 2 Pharmacokinetics)

1、 问题:How drug transport across membranes?
评分规则: 【 1. Passive transport    1)diffusion of unionized drugs     2) diffusion of drugs of weak electrolytes         3) Filtration (Aqueous diffusion)     4) Facilitated diffusion2. Active transport 

Chapter 2 Pharmacokinetics Quiz (Chapter 2 Pharmacokinetics)

1、 问题:Most drugs enter the body by one of the following mechanisms 
选项:
A:facilited diffusion
B:simple diffusion
C:active transport
D: filtration
答案: 【simple diffusion

2、 问题:Active transport is characterized by (    )
选项:
A:Transport by carrier, no energy is required
B:Through carrier transport, energy is required
C:No carrier transport, no energy consumption
D:Without carrier transport, energy is required
答案: 【Through carrier transport, energy is required

3、 问题:Easy diffusion is 
选项:
A:Transmembrane transport by carrier against concentration gradient
B:No carrier, trans-membrane transport along concentration gradient
C:Relying on the carrier, trans-membrane transport along the concentration gradient
D:simple diffusion
答案: 【Relying on the carrier, trans-membrane transport along the concentration gradient

4、 问题:Which of the following statements about active drug transport is false
选项:
A:It takes energy
B:Can be disturbed by other chemicals
C:Chemical structure specificity
D:Equilibrium is reached faster than passive transport
答案: 【Equilibrium is reached faster than passive transport

5、 问题:Which of the following statements about oral administration is false
选项:
A:After absorption, it enters the liver via the portal vein
B:Absorption is rapid and complete
C:There is first pass elimination
D:The small intestine is the main site of absorption
答案: 【Absorption is rapid and complete

6、 问题:The administration route of the first pass elimination  is
选项:
A:rectal administration
B:sublingual administration
C:intravenous administration
D:oral medication
答案: 【oral medication

7、 问题:The drug enters the bloodstream, first (    )
选项:
A:It ACTS on the target organ
B:Metabolize in the liver
C:Excretion in the kidney
D:Binds to plasma proteins
答案: 【Binds to plasma proteins

8、 问题:Fluid pH affects drug transport and distribution because it alters the drug (     )
选项:
A:water solubility
B:lipid solubility
C:pKa
D:degree of dissociation
答案: 【degree of dissociation

9、 问题:A drug that does not directly cause its effect is 
选项:
A:A drug that is metabolized by the liver
B:A drug that binds to a plasma protein
C:Drugs in the circulation of blood
D:Medications that reach the bladder
答案: 【A drug that binds to a plasma protein

10、 问题:Liver drug enzymes are characterized by 
选项:
A:Limited activity, high specificity, large individual differences
B:High activity, high specificity, large individual differences
C:High activity, high specificity, small individual differences
D:Limited activity, low specificity, large individual differences
答案: 【Limited activity, low specificity, large individual differences

【作业】Chapter 3 Pharmacodynamics Homework(Chapter 3 Pharmacodynamics)

1、 问题:Describe the similarities and differences between potency and efficacy
评分规则: 【 similarity: both are the parameters to describe the pharmacodynamics characteristics of drugs
difference:potency means the dose with same effects efficacy means the maximum effects of one drug

Chapter 3 Pharmacodynamics Quiz (Chapter 3 Pharmacodynamics)

1、 问题:The intrinsic activity (effect) of the drug refers to   

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